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Gastrointestinal, Gastroesophageal reflux disease (GERD), gastro-oesophageal reflux disease (GORD), gastric reflux disease, or acid reflux disease is defined as chronic symptoms or mucosal damage produced by the abnormal reflux in the esophagus.
One in 10 Americans experiences heartburn symptoms at least once a week. Heartburn has different triggers, including certain foods, medications, obesity, or even stress. Acid reflux is common, but chronic acid reflux (Gastroesophageal Reflux Disease) can become a real problem.
At the entrance to the stomach is a valve called lower esophageal sphincter (LES). The LES should close as soon as food enters the stomach so that no food can splash back up into the esophagus, however, if the LES does not close properly or if it opens often, stomach acid can move into the esophagus and cause heartburn. There are various causes including hiatal hernias, eating foods containing high amounts of acid (citrus, coffee, tomato, chocolate, or spicy or fatty foods), and drinking alcohol.
Typically, GERD is treated with prescription or over the counter medications. These prescriptions can have side effects such as nausea, headache, diarrhea, gas, bloating, constipation, and stomach pain. Cannabinoids can be effective against these side effects, but it can also improve acid reflux in general.
It has been found that “Activation of cannabinoid receptors (CB(1), CB(2) and GPR(55)) produces analgesic effects in several experimental pain models, including visceral pain arising from the gastrointestinal tract” in one study at AstraZeneca R&D Mölndal in Sweden.
At the Department of Experimental Pharmacology at the University of Naples in Italy also conducted research on gastrointestinal problems: “Salvinorin A, the active component of the hallucinogenic herb Salvia divinorum, inhibits intestinal motility through activation of kappa-opioid receptors (KORs). However, this compound may have target(s) other than the KORs in the inflamed gut. Because intestinal inflammation upregulates cannabinoid receptors and endogenous cannabinoids, in the present study we investigated the possible involvement of the endogenous cannabinoid system in salvinorin A-induced delay in motility in the inflamed gut.” The study concluded, “The inhibitory effect of salvinorin A on motility reveals a functional interaction between cannabinoid CB(1) receptors and KORs in the inflamed-but not in the normal-gut in vivo.”
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Category
Critical Ailments -
Created
Thursday, 30 November 2017 -
Group admin
CBIS
American States University
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ALL of your PREVIOUS Cannabis Science (CBIS) Shares are on Record with the Company and with the Transfer Agent (As Confirmed by the SEC).
The Company does NOT have your Original trading CBIS Shares, either you have them, or your Brokerage Firm has them (with new identifier codes) or the Transfer Agent has them.
You can confirm with your Broker (Please obtain an Official Brokerage Firm Letter Representing where your CBIS shares are).
Your CBIS GIFT Shares are on Record Books with the Company and/or in your possesion for Regulatory submissions, Registered Legal Opinion Letters, and awaiting Final Audit for Final Trading approvals.
Your CBIS Shares are legal tender and we are ALL waiting for the FINAL Confirmations for trading once the Audits and Legal Filings are completed.
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This is More than enough Funding to begin our FDA Clinical Trials for our 'Low-Cost Cancer Drugs' to treat millions Worldwide that already has proven HARVARD Award Winning Cancer Killing Success!
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This is also PLENTY of Funding to bring ALL our CBIS Shares back trading again and follow through with our Original Complete Cannabis Science Share trading Game Plan, and We Win, once again. Hopefully we'll see you at the Event to help 'Make that Change'!"
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The ASU Digital Business HUB will be used as the main business student learning center. GBXI will be the main pivot point to spin out trading shares of all our Partner Public and Private Companies such as Cannabis Science, iCannabinoid, Thermic Science, LNC, LMG, and a few more old and new school surprises for our loyal shareholders. No one will be missed! A true Digital Business HUB for students, just as planned all along.
Each spinout company will give our GBXI registered shareholders additional pro-rata shares in each spinout company over and above their original shares in each entity. This provides the required shareholder base for each company required to trade and gives additional shares to all our loyal GBXI shareholders.
We call this “Compounding our Wealth” through extra spinout share participation for all our loyal GBXI shareholders. Each registered GBXI shareholder will receive additional shares of each spinout Company over and above their original shares to enjoy additional liquidity as each company begins to trade through the GBXI Digital Business HUB spinout process.
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Still sitting on CBIS shares... what gives?
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Investor Relations
Investor Relations
Adding investor value is of paramount importance to Cannabis Science. One way we do this is to service potential and existing shareholders. We are...
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2023 Audit considerations NASDAQ.
Cannabis Science Inc.
Share Structure 2023
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Last Price: $0.00647 USD
OTC Markets.
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Authorized:
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